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Produced by Type II alveolar epithelial cells.DPPC is amphipathic (charged choline head, hydrophobic.Surfactant is mainly phospholipid (dipalmitoyl phosphatidylcholine DPPC), some protein and carbohydrate.T - surface tension along the surface of the sphere.
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Laplace's Law: P = 4 x T / r (for a sphere).Surfactant dramatically reduces surface tension.High surface tension of liquid lining the alveoli tends to collapse them.Separates abdominal and thoracic contents.Peripheral afferents from intercostal and subcostal nerves.Efferent and central afferent: phrenic nerve (C3-5).Back attaches to T12 vertebral body, descents to L1/L2 on sides.Front arises from xiphoid process, costal margins.3 Openings: Aorta (T12), oesophagus (T10) and vena caval (T8).
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